DDI Publications List

Akhter N, Hasan A, Shenouda S, Wilson A, Kochumon S, Ali S, Tuomilehto J, Sindhu S, Ahmad R. TLR4/MyD88 -mediated CCL2 production by lipopolysaccharide (endotoxin): Implications for metabolic inflammation. J Diabetes Metab Disord. 2018; 341

Ahmad R, Al-Roub A, Kochumon S, Akther N, Thomas R, Kumari M, Koshy MS, Tiss A, Hannun YA, Tuomilehto J, Sindhu S, Rosen ED. The Synergy between Palmitate and TNF-? for CCL2 Production Is Dependent on the TRIF/IRF3 Pathway: Implications for Metabolic Inflammation. J Immunol. 200(10):3599-3611.

Taha NA, Rahme Z, Mesbah N, Mahmoud F, AlKandari S, Othman N, Sharaikha H, Lari BS, AlBeloushi S, Saad E, Arefanian H, Sukkar FF. Evaluation of the Impact of a Diabetes Education eLearning Program for School Personnel on Diabetes Knowledge, Knowledge Retention and Confidence in Caring for Students with Diabetes. Diabetes Res Clin Pract. 2018; pii: S0168-8227(18)30015-9.

Tabesh M, Shaw JE, Zimmet PZ, Soderberg S, Koye DN, Kowlessur S, Timol M, Joonas N, Sorefan A, Gayan P, Alberti KGMM, Tuomilehto J, Magliano DJ. The association between type 2 diabetes and disability: what is the contribution of diabetes risk factors and diabetes complications? Early view: J Diabetes. 2018. doi.org/10.1111/1753-0407.12659

NCD Risk Factor Collaboration (NCD-RisC)…Tuomilehto J. et al. Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants. Int J Epidemiol. 2018; 1–21

Kochumon S,  Wilson A, Chandy B,  Shenouda S, Tuomilehto J, Sindhu S, Ahmad R.  Palmitate Activates CCL4 Expression in Human Monocytic Cells via TLR4/MyD88 Dependent Activation of NF-?B/MAPK/ PI3K Signaling Systems. Cell Physiol Biochem. 2018;46(3):953-964.

Gilis-Januszewska A, Barengo NC, Lindstrom J, Wojtowicz E, Acosta T, Tuomilehto J, Schwarz PEH, Piwo?ska-Solska B, Szybinski Z, Windak A, Hubalewska-Dydejczyk A. Predictors of long term weight loss maintenance in patients at high risk of type 2 diabetes participating in a lifestyle intervention program in primary health care: The DE-PLAN study. PLoS One. 2018;13(3):e0194589.

Cornelis MC, Erlund I, Michelotti GA, Herder C, Westerhuis JA, Tuomilehto J. Metabolomic response to coffee consumption: application to a three-stage clinical trial. Early view: J Intern Med. 2018; doi.org/10.1111/joim.12737

Ali F, Alsayegh F, Sharma P, Waheedi M, Bayoud T, Alrefai F. White blood cell subpopulation changes and prevalence of neutropenia among Arab diabetic patients attending Dasman Diabetes Institute in Kuwait. PLoS One. 2018;13(3):e0193920.

Abu-Farha M, Cherian P, Qaddoumi MG, AlKhairi I, Sriraman D, Alanbaei M, Abubaker J. Increased plasma and adipose tissue levels of ANGPTL8/Betatrophin and ANGPTL4 in people with hypertension. Lipids Health Dis. 2018;17(1):35

Gilis-Januszewska A, Lindstrom J, Barengo NC, Tuomilehto J, Schwarz PE, Wojtowicz E, Piwonska-Solska B, Szybinski Z, Windak A, Hubalewska-Dydejczyk A. Predictors of completing a primary health care diabetes prevention intervention programme in people at high risk of type 2 diabetes: Experiences of the DE-PLAN project. Medicine (Baltimore). 2018;97(5):e9790

Dahlqvist S, Ahlen E, Filipsson K, Gustafsson T, Hirsch IB, Tuomilehto J, Imberg H, Ahren B, Attvall S, Lind M. Variables associated with HbA1c and weight reductions when adding liraglutide to multiple daily insulin injections in persons with type 2 diabetes (MDI Liraglutide trial 3). BMJ Open Diabetes Res Care. 2018;6(1):e000464.

Bertoli-Avella AM, Garcia-Aznar JM, Al-Mulla F, Rolfs Abauer P. Biallelic inactivating variants in the GTPBP2 gene cause a neurodevelopmental disorder with severe intellectual disability. Online First: Eur J Hum Genet. 2018; doi:10.1038/s41431-018-0097-3

Al-Serri A, Al-Bustan S.A, Kamkar M, Thomas D, Al-Smaidi O, Al-Temaimi R, Mojiminiyi O.A, Abdella N. Association of FTO rs9939609 with Obesity in The Kuwaiti Population: A Public Health Concern?. Med Princ Pract. 2018; doi: 10.1159/000486767.

Al Madhoun A, Alkandari S, Ali H, Carrio N, Atari M, Bitar MS, Al-Mulla F. Chemically Defined Conditions Mediate an Efficient Induction of Mesodermal Lineage from Human Umbilical Cord- and Bone Marrow- Mesenchymal Stem Cells and Dental Pulp Pluripotent-Like Stem Cells. Cell Reprogram. 2018;20(1):9-16

Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T, Giri A, Graff M…Tuomilehto J. et al. Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nat Genet. 2018;50(1):26-41.

Solomon A, Turunen H, Ngandu T, Peltonen M, Levalahti E, Helisalmi S, Antikainen R, Backman L, Hanninen T, Jula A,... Tuomilehto J, et al. Effect of the Apolipoprotein E Genotype on Cognitive Change During a Multidomain Lifestyle Intervention: A Subgroup Analysis of a Randomized Clinical Trial. online first JAMA Neurol. 2018; doi: 10.1001/jamaneurol.2017.4365

Sindhu S, Akhter N, Kochumon S, Thomas R, Wilson A, Shenouda S, Tuomilehto J, Ahmad R. Increased Expression of the Innate Immune Receptor TLR10 in Obesity and Type-2 Diabetes: Association with ROS-Mediated Oxidative Stress. Cell Physiol Biochem. 2018;45:572-590.

Shahim B, Gyberg V, De Bacquer D, Kotseva K, De Backer G, Schnell O, Tuomilehto J, Wood D, Ryden L. Undetected dysglycaemia common in primary care patients treated for hypertension and/or dyslipidaemia: on the need for a screening strategy in clinical practice. A report from EUROASPIRE IV a registry from the EuroObservational Research Programme of the European Society of Cardiology. Cardiovasc Diabetol. 2018;17(1):21.

Mezzavilla M, Tomei S, Alkayal F, Melhem M, Ali MM, Al-Arouj M, Bennakhi A, Alsmadi O, Elkum N. Investigation of genetic variation and lifestyle determinants in vitamin D levels in Arab individuals. J Transl Med. 2018;16(1):20.