DDI Publications List

Alsaeed D, Orlu M, Smith F. Optimising Medication Use along Dementia Progression: Recommendations from a Qualitative Study. Healthcare (Basel). 2021 Aug 2;9(8):982. doi: 10.3390/healthcare9080982. PMID: 34442119; PMCID: PMC8391125.

Al-Kandari H, Al-Abdulrazzaq D, Davidsson L, Nizam R, Jacob S, Melhem M, John SE, Al-Mulla F. Identification of Maturity-Onset-Diabetes of the Young (MODY) mutations in a country where diabetes is endemic. Sci Rep. 2021 Aug 9;11(1):16060. doi: 10.1038/s41598-021-95552-z. PMID: 34373539; PMCID:PMC8352960.

Rahman A, Hammad MM, Al Khairi I, Cherian P, Al-Sabah R, Al-Mulla F, Abu- Farha M, Abubaker J. Profiling of Insulin-Like Growth Factor Binding Proteins (IGFBPs) in Obesity and Their Association With Ox-LDL and Hs-CRP in Adolescents. Front Endocrinol (Lausanne). 2021 Jul 28;12:727004. doi: 10.3389/fendo.2021.727004. PMID: 34394011; PMCID: PMC8355984.

Al-Roub A, Akhter N, Al-Sayyar A, Wilson A, Thomas R, Kochumon S, Al-Rashed F, Al-Mulla F, Sindhu S, Ahmad R. Short Chain Fatty Acid Acetate Increases TNFα- Induced MCP-1 Production in Monocytic Cells via ACSL1/MAPK/NF-κB Axis. Int J Mol Sci. 2021 Jul 19;22(14):7683. doi: 10.3390/ijms22147683. PMID: 34299302; PMCID: PMC8304091.

Al-Rashed F, Sindhu S, Al Madhoun A, Ahmad Z, AlMekhled D, Azim R, Al- Kandari S, Wahid MA, Al-Mulla F, Ahmad R. Elevated resting heart rate as a predictor of inflammation and cardiovascular risk in healthy obese individuals. Sci Rep. 2021 Jul 6;11(1):13883. doi: 10.1038/s41598-021-93449-5. PMID: 34230580; PMCID: PMC8260607.

Mohammad A, Abubaker J, Al-Mulla F. Structural modelling of SARS-CoV-2 alpha variant (B.1.1.7) suggests enhanced furin binding and infectivity. Virus Res. 2021 Jul 24;303:198522. doi: 10.1016/j.virusres.2021.198522. Epub ahead of print. PMID: 34314772; PMCID: PMC8310422.

Al-Rashed F, Sindhu S, Al Madhoun A, Alghaith A, Azim R, Al-Mulla F, Ahmad R. Short Sleep Duration and Its Association with Obesity and Other Metabolic Risk Factors in Kuwaiti Urban Adults. Nat Sci Sleep. 2021 Jul 24;13:1225-1241. doi: 10.2147/NSS.S311415. PMID: 34335063; PMCID: PMC8318215.

Kavalakatt S, Khadir A, Madhu D, Koistinen HA, Al-Mulla F, Tuomilehto J, Abubaker J, Tiss A. Urocortin 3 overexpression reduces ER stress and heat shock response in 3T3-L1 adipocytes. Sci Rep. 2021 Aug 2;11(1):15666. doi: 10.1038/s41598-021-95175-4. PMID: 34341463; PMCID: PMC8329193.

Possik E, Al-Mass A, Peyot ML, Ahmad R, Al-Mulla F, Madiraju SRM, Prentki M. New Mammalian Glycerol-3-Phosphate Phosphatase: Role in β-Cell, Liver and Adipocyte Metabolism. Front Endocrinol (Lausanne). 2021 Jul 13;12:706607. doi: 10.3389/fendo.2021.706607. PMID: 34326816; PMCID: PMC8313997.

Taher I, Almaeen A, Ghazy A, Abu-Farha M, Mohamed Channanath A, Elsa John S, Hebbar P, Arefanian H, Abubaker J, Al-Mulla F, Alphonse Thanaraj T. Relevance Between COVID-19 and Host Genetics of Immune Response. Saudi J Biol Sci. 2021 Jul 17. doi: 10.1016/j.sjbs.2021.07.037. Epub ahead of print. PMID: 34305429; PMCID: PMC8285220.

Adler A, Bennett P, Colagiuri Chair S, Gregg E, Venkat Narayan KM, Inês Schmidt M, Sobngwi E, Tajima N, Tandon N, Unwin N, Wild S, Yudkin J, Levitt N, Mohan V, Montgomery S, Nyirenda MJ, Tuomilehto J, Den Boon S, Hocking S. REPRINT OF: CLASSIFICATION OF DIABETES MELLITUS. Diabetes Res Clin Pract. 2021 Jul 31:108972. doi: 10.1016/j.diabres.2021.108972. Epub ahead of print. PMID: 34343595.

Alwosais EZM, Al-Ozairi E, Zafar TA, Alkandari S. Chia seed (Salvia hispanica L.) supplementation to the diet of adults with type 2 diabetes improved systolic blood pressure: A randomized controlled trial. Nutr Health. 2021 Jun;27(2):181-189. doi: 10.1177/0260106020981819. Epub 2021 Feb 2. PMID: 33530854.

Mohammad A, Al-Mulla F, Wei DQ, Abubaker J. Remdesivir MD Simulations Suggest a More Favourable Binding to SARS-CoV-2 RNA Dependent RNA Polymerase Mutant P323L Than Wild-Type. Biomolecules. 2021 Jun 22;11(7):919. doi:10.3390/biom11070919. PMID: 34206274.

Alqaderi H, Ramakodi MP, Nizam R, Jacob S, Devarajan S, Eaaswarkhanth M, Al-Mulla F. Salivary Microbiome Diversity in Kuwaiti Adolescents with Varied Body Mass Index—A Pilot Study. Microorganisms. 2021 Jun 4;9(6):1222. doi: 10.3390/microorganisms9061222. PMCID: PMC8228046.

Khan A, Wei DQ, Kousar K, Abubaker J, Ahmad S, Ali J, Al-Mulla F, Ali SS,Nizam-Uddin N, Mohammad Sayaf A, Mohammad A. Preliminary Structural Data Revealed That the SARS-CoV-2 B.1.617 Variant's RBD Binds to ACE2 ReceptorStronger Than the Wild Type to Enhance the Infectivity. Chembiochem. 2021 Aug17;22(16):2641-2649. doi: 10.1002/cbic.202100191. Epub 2021 Jul 5. PMID:34160124.

Al Madhoun A, Haddad D, Al Tarrah M, Jacob S, Al-Ali W, Nizam R, Miranda L, Al-Rashed F, Sindhu S, Ahmad R, Bitar MS, Al-Mulla F. Microarray analysis reveals ONC201 mediated differential mechanisms of CHOP gene regulation in metastatic and nonmetastatic colorectal cancer cells. Sci Rep. 2021 Jun 4;11(1):11893. doi: 10.1038/s41598-021-91092-8. PMID: 34088951; PMCID: PMC8178367.

Khan A, Khan S, Saleem S, Nizam-Uddin N, Mohammad A, Khan T, Ahmad S, Arshad M, Ali SS, Suleman M, Wei DQ. Immunogenomics guided design of immunomodulatory multi-epitope subunit vaccine against the SARS-CoV-2 new variants, and its validation through in silico cloning and immune simulation. Comput Biol Med. 2021 Jun;133:104420. doi: 10.1016/j.compbiomed.2021.104420. Epub 2021 Apr 24. PMID: 33930764; PMCID: PMC8064902.

Hassanein M, Al Sifri S, Shaikh S, Raza SA, Akram J, Rudijanto A, Shaltout I, Fariduddin M, Mohamed WMIBW, Al Awadi F, Durocher A, Cortese V, Alessa T. Descriptive Regional Subanalysis of a Real-World Study in Patients with Type 2 Diabetes Treated with Gliclazide MR During Fasting: DIA-RAMADAN. Diabetes Ther. 2021 Jun;12(6):1703-1719. doi: 10.1007/s13300-021-01067-1. Epub 2021 May 11. PMID: 33974216; PMCID: PMC8179867.

Gomez-Peralta F, Al-Ozairi E, Jude EB, Li X, Rosenstock J. Titratable fixed- ratio combination of basal insulin plus a glucagon-like peptide-1 receptor agonist: A novel, simplified alternative to premix insulin for type 2 diabetes. Diabetes Obes Metab. 2021 Jul;23(7):1445-1452. doi: 10.1111/dom.14365. Epub 2021 Mar 31. PMID: 33651460.

Al-Saleh Y, Sabico S, Al-Furqani A, Jayyousi A, Alromaihi D, Ba-Essa E, Alawadi F, Alkaabi J, Hassanein M, Al-Sifri S, Saleh S, Alessa T, Al-Daghri NM. Sulfonylureas in the Current Practice of Type 2 Diabetes Management: Are They All the Same?Consensus from the Gulf Cooperation Council (GCC) CountriesAdvisory Board on Sulfonylureas. Diabetes Ther. 2021 Aug;12(8):2115-2132. doi: 10.1007/s13300-021-01059-1. Epub 2021 May 13. Erratum in: Diabetes Ther. 2021 Jul 23;: PMID: 33983614.